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2170240-91-0

2170240-91-0 structure
2170240-91-0 structure
  • Name: Azido-PEG3-aminoacetic acid-NHS ester
  • Chemical Name: Azido-PEG3-aminoacetic acid-NHS ester
  • CAS Number: 2170240-91-0
  • Molecular Formula: C14H23N5O7
  • Molecular Weight: 373.36
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 18:29:26
  • Modify Date: 2024-01-03 17:27:16
  • Azido-PEG3-aminoacetic acid-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Azido-PEG3-aminoacetic acid-NHS ester
Description Azido-PEG3-aminoacetic acid-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C14H23N5O7
Molecular Weight 373.36