Azido-PEG3-aminoacetic acid-NHS ester

Modify Date: 2024-01-03 17:27:16

Azido-PEG3-aminoacetic acid-NHS ester Structure
Azido-PEG3-aminoacetic acid-NHS ester structure
Common Name Azido-PEG3-aminoacetic acid-NHS ester
CAS Number 2170240-91-0 Molecular Weight 373.36
Density N/A Boiling Point N/A
Molecular Formula C14H23N5O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG3-aminoacetic acid-NHS ester


Azido-PEG3-aminoacetic acid-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG3-aminoacetic acid-NHS ester

 Azido-PEG3-aminoacetic acid-NHS ester Biological Activity

Description Azido-PEG3-aminoacetic acid-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C14H23N5O7
Molecular Weight 373.36