2144777-77-3

2144777-77-3 structure
2144777-77-3 structure
  • Name: Azido-PEG5-CH2CO2-NHS
  • Chemical Name: Azido-PEG5-CH2CO2-NHS
  • CAS Number: 2144777-77-3
  • Molecular Formula: C16H26N4O9
  • Molecular Weight: 418.40
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 09:39:47
  • Modify Date: 2024-01-09 16:34:54
  • Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Azido-PEG5-CH2CO2-NHS
Description Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C16H26N4O9
Molecular Weight 418.40
Hazard Codes Xi