2100306-68-9

2100306-68-9 structure
2100306-68-9 structure
  • Name: Benzyloxy carbonyl-PEG3-NHS ester
  • Chemical Name: Benzyloxy carbonyl-PEG3-NHS ester
  • CAS Number: 2100306-68-9
  • Molecular Formula: C21H27NO9
  • Molecular Weight: 437.44
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 19:51:20
  • Modify Date: 2024-01-16 18:32:28
  • Benzyloxy carbonyl-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Benzyloxy carbonyl-PEG3-NHS ester
Synonyms MFCD30723240
Description Benzyloxy carbonyl-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C21H27NO9
Molecular Weight 437.44
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