Benzyloxy carbonyl-PEG3-NHS ester

Modify Date: 2024-01-16 18:32:28

Benzyloxy carbonyl-PEG3-NHS ester Structure
Benzyloxy carbonyl-PEG3-NHS ester structure
Common Name Benzyloxy carbonyl-PEG3-NHS ester
CAS Number 2100306-68-9 Molecular Weight 437.44
Density N/A Boiling Point N/A
Molecular Formula C21H27NO9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Benzyloxy carbonyl-PEG3-NHS ester


Benzyloxy carbonyl-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Benzyloxy carbonyl-PEG3-NHS ester
Synonym More Synonyms

 Benzyloxy carbonyl-PEG3-NHS ester Biological Activity

Description Benzyloxy carbonyl-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C21H27NO9
Molecular Weight 437.44

 Synonyms

MFCD30723240
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