1260247-50-4

1260247-50-4 structure
1260247-50-4 structure
  • Name: Biotin-PEG4-amino-t-Bu-DADPS-C6-azide
  • Chemical Name: Biotin-PEG4-amino-t-Bu-DADPS-C6-azide
  • CAS Number: 1260247-50-4
  • Molecular Formula: C43H67N7O9SSi
  • Molecular Weight: 886.18
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 17:21:33
  • Modify Date: 2024-01-09 17:02:20
  • Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Biotin-PEG4-amino-t-Bu-DADPS-C6-azide
Description Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C43H67N7O9SSi
Molecular Weight 886.18
Hazard Codes Xi