Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Biotin-peg8-nhs ester
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

2143968-03-8

2143968-03-8 structure

2143968-03-8 structure

Name: Biotin-PEG8-NHS ester
Chemical Name: Biotin-PEG8-NHS ester
CAS Number: 2143968-03-8
Molecular Formula: C₃₃H₅₆N₄O₁₄S
Molecular Weight: 764.88
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 21:01:37
Modify Date: 2024-01-18 09:36:59
Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Biotin-PEG8-NHS ester
Synonyms	MFCD27977502

Description	Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₃H₅₆N₄O₁₄S
Molecular Weight	764.88