2143968-03-8

2143968-03-8 structure
2143968-03-8 structure
  • Name: Biotin-PEG8-NHS ester
  • Chemical Name: Biotin-PEG8-NHS ester
  • CAS Number: 2143968-03-8
  • Molecular Formula: C33H56N4O14S
  • Molecular Weight: 764.88
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 21:01:37
  • Modify Date: 2024-01-18 09:36:59
  • Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Biotin-PEG8-NHS ester
Synonyms MFCD27977502
Description Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C33H56N4O14S
Molecular Weight 764.88