Biotin-PEG8-NHS ester

Modify Date: 2024-01-18 09:36:59

Biotin-PEG8-NHS ester structure	Common Name	Biotin-PEG8-NHS ester
	CAS Number	2143968-03-8	Molecular Weight	764.88
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₃H₅₆N₄O₁₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Biotin-PEG8-NHS ester

Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Biotin-PEG8-NHS ester
Synonym	More Synonyms

Description	Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₃H₅₆N₄O₁₄S
Molecular Weight	764.88

MFCD27977502