Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Bis-PEG17-acid
Price:
Purity: 95.0%
Stocking Period: 10 Day
Contact: Yang

2226897-74-9

2226897-74-9 structure

2226897-74-9 structure

Name: Bis-PEG17-acid
Chemical Name: Bis-PEG17-acid
CAS Number: 2226897-74-9
Molecular Formula: C₃₈H₇₄O₂₁
Molecular Weight: 866.98
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 19:22:00
Modify Date: 2024-09-01 19:23:52
Bis-PEG17-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Bis-PEG17-acid

Description	Bis-PEG17-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₈H₇₄O₂₁
Molecular Weight	866.98