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2183440-31-3

2183440-31-3 structure
2183440-31-3 structure
  • Name: t-Boc-N-Amido-PEG8-propargyl
  • Chemical Name: Boc-NH-PEG8-propargyl
  • CAS Number: 2183440-31-3
  • Molecular Formula: C24H45NO10
  • Molecular Weight: 507.61
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-02 07:19:07
  • Modify Date: 2024-01-08 21:20:04
  • Boc-NH-PEG8-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Boc-NH-PEG8-propargyl
Synonyms MFCD31561113
Description Boc-NH-PEG8-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C24H45NO10
Molecular Weight 507.61