t-Boc-N-Amido-PEG8-propargyl

Modify Date: 2024-01-08 21:20:04

t-Boc-N-Amido-PEG8-propargyl Structure
t-Boc-N-Amido-PEG8-propargyl structure
Common Name t-Boc-N-Amido-PEG8-propargyl
CAS Number 2183440-31-3 Molecular Weight 507.61
Density N/A Boiling Point N/A
Molecular Formula C24H45NO10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-Boc-N-Amido-PEG8-propargyl


Boc-NH-PEG8-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Boc-NH-PEG8-propargyl
Synonym More Synonyms

 t-Boc-N-Amido-PEG8-propargyl Biological Activity

Description Boc-NH-PEG8-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C24H45NO10
Molecular Weight 507.61

 Synonyms

MFCD31561113