932741-11-2

932741-11-2 structure

932741-11-2 structure

Name: Bromoacetamide-PEG3-propargyl
Chemical Name: Bromoacetamide-PEG3-propargyl
CAS Number: 932741-11-2
Molecular Formula: C₁₁H₁₈BrNO₄
Molecular Weight: 308.17
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 18:20:21
Modify Date: 2023-05-17 10:00:06
Bromoacetamide-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Bromoacetamide-PEG3-propargyl

Description	Bromoacetamide-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₁H₁₈BrNO₄
Molecular Weight	308.17