Bromoacetamide-PEG3-propargyl

Modify Date: 2024-07-18 10:08:10

Bromoacetamide-PEG3-propargyl Structure
Bromoacetamide-PEG3-propargyl structure
Common Name Bromoacetamide-PEG3-propargyl
CAS Number 932741-11-2 Molecular Weight 308.17
Density N/A Boiling Point N/A
Molecular Formula C11H18BrNO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromoacetamide-PEG3-propargyl


Bromoacetamide-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bromoacetamide-PEG3-propargyl

 Bromoacetamide-PEG3-propargyl Biological Activity

Description Bromoacetamide-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C11H18BrNO4
Molecular Weight 308.17