2353410-19-0

2353410-19-0 structure
2353410-19-0 structure
  • Name: Bromoacetamido-PEG5-DOTA
  • Chemical Name: Bromoacetamido-PEG5-DOTA
  • CAS Number: 2353410-19-0
  • Molecular Formula: C30H55BrN6O13
  • Molecular Weight: 787.69
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 10:21:31
  • Modify Date: 2024-01-27 08:25:40
  • Bromoacetamido-PEG5-DOTA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bromoacetamido-PEG5-DOTA
Description Bromoacetamido-PEG5-DOTA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C30H55BrN6O13
Molecular Weight 787.69