Bromoacetamido-PEG5-DOTA

Modify Date: 2024-01-27 08:25:40

Bromoacetamido-PEG5-DOTA Structure
Bromoacetamido-PEG5-DOTA structure
Common Name Bromoacetamido-PEG5-DOTA
CAS Number 2353410-19-0 Molecular Weight 787.69
Density N/A Boiling Point N/A
Molecular Formula C30H55BrN6O13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromoacetamido-PEG5-DOTA


Bromoacetamido-PEG5-DOTA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bromoacetamido-PEG5-DOTA

 Bromoacetamido-PEG5-DOTA Biological Activity

Description Bromoacetamido-PEG5-DOTA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C30H55BrN6O13
Molecular Weight 787.69
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