1446282-35-4

1446282-35-4 structure
1446282-35-4 structure

Name C6-Bis-phosphoramidic acid diethyl ester
Synonyms MFCD25424109
Description C6-Bis-phosphoramidic acid diethyl ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C14H34N2O6P2
Molecular Weight 388.38