1446282-35-4

1446282-35-4 structure

1446282-35-4 structure

Name: [6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester
Chemical Name: C6-Bis-phosphoramidic acid diethyl ester
CAS Number: 1446282-35-4
Molecular Formula: C₁₄H₃₄N₂O₆P₂
Molecular Weight: 388.38
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-02 07:18:44
Modify Date: 2024-01-07 18:52:35
C6-Bis-phosphoramidic acid diethyl ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	C6-Bis-phosphoramidic acid diethyl ester
Synonyms	MFCD25424109

Description	C6-Bis-phosphoramidic acid diethyl ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl-Chain
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₄H₃₄N₂O₆P₂
Molecular Weight	388.38