[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester

Modify Date: 2024-01-07 18:52:35

[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester Structure
[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester structure
Common Name [6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester
CAS Number 1446282-35-4 Molecular Weight 388.38
Density N/A Boiling Point N/A
Molecular Formula C14H34N2O6P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of [6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester


C6-Bis-phosphoramidic acid diethyl ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name C6-Bis-phosphoramidic acid diethyl ester
Synonym More Synonyms

  Biological Activity

Description C6-Bis-phosphoramidic acid diethyl ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C14H34N2O6P2
Molecular Weight 388.38

 Synonyms

MFCD25424109
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