Shanghai Nianxing Industrial Co., Ltd
China
Product Name: DBCO-NH-Boc
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Purity: 98.0%
Stocking Period: 10 Day
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1539290-74-8

1539290-74-8 structure

1539290-74-8 structure

Name: DBCO-NH-Boc
Chemical Name: DBCO-NH-Boc
CAS Number: 1539290-74-8
Molecular Formula: C₂₃H₂₄N₂O₃
Molecular Weight: 376.45
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 13:26:31
Modify Date: 2025-10-10 18:55:33
DBCO-NH-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	DBCO-NH-Boc
Synonyms	MFCD31693716

Description	DBCO-NH-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₃H₂₄N₂O₃
Molecular Weight	376.45

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