DBCO-NH-Boc

Modify Date: 2025-10-10 18:55:33

DBCO-NH-Boc structure	Common Name	DBCO-NH-Boc
	CAS Number	1539290-74-8	Molecular Weight	376.45
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₄N₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of DBCO-NH-Boc

DBCO-NH-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	DBCO-NH-Boc
Synonym	More Synonyms

Description	DBCO-NH-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₃H₂₄N₂O₃
Molecular Weight	376.45

MFCD31693716

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