2112737-94-5

2112737-94-5 structure
2112737-94-5 structure
  • Name: DSPE-PEG8-Mal
  • Chemical Name: DSPE-PEG8-Mal
  • CAS Number: 2112737-94-5
  • Molecular Formula: C64H119N2O19P
  • Molecular Weight: 1251.61
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-02 07:03:55
  • Modify Date: 2024-01-17 13:08:49
  • DSPE-PEG8-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name DSPE-PEG8-Mal
Description DSPE-PEG8-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C64H119N2O19P
Molecular Weight 1251.61