DSPE-PEG8-Mal

Modify Date: 2024-01-17 13:08:49

DSPE-PEG8-Mal Structure
DSPE-PEG8-Mal structure
Common Name DSPE-PEG8-Mal
CAS Number 2112737-94-5 Molecular Weight 1251.61
Density N/A Boiling Point N/A
Molecular Formula C64H119N2O19P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DSPE-PEG8-Mal


DSPE-PEG8-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name DSPE-PEG8-Mal

 DSPE-PEG8-Mal Biological Activity

Description DSPE-PEG8-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C64H119N2O19P
Molecular Weight 1251.61