2291257-76-4

2291257-76-4 structure
2291257-76-4 structure
  • Name: Fmoc-NH-PEG12-CH2COOH
  • Chemical Name: Fmoc-NH-PEG12-CH2COOH
  • CAS Number: 2291257-76-4
  • Molecular Formula: C41H63NO16
  • Molecular Weight: 825.94
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 23:35:33
  • Modify Date: 2024-01-04 12:52:12
  • Fmoc-NH-PEG12-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Fmoc-NH-PEG12-CH2COOH
Synonyms MFCD30723256
Description Fmoc-NH-PEG12-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C41H63NO16
Molecular Weight 825.94