Fmoc-NH-PEG12-CH2COOH

Modify Date: 2025-09-18 17:56:25

Fmoc-NH-PEG12-CH2COOH Structure
Fmoc-NH-PEG12-CH2COOH structure
Common Name Fmoc-NH-PEG12-CH2COOH
CAS Number 2291257-76-4 Molecular Weight 825.94
Density N/A Boiling Point N/A
Molecular Formula C41H63NO16 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Fmoc-NH-PEG12-CH2COOH


Fmoc-NH-PEG12-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Fmoc-NH-PEG12-CH2COOH
Synonym More Synonyms

 Fmoc-NH-PEG12-CH2COOH Biological Activity

Description Fmoc-NH-PEG12-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C41H63NO16
Molecular Weight 825.94
InChIKey YZIUMHBWFVGVKQ-UHFFFAOYSA-N
SMILES O=C(O)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21

 Synonyms

MFCD30723256
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