2228857-30-3

2228857-30-3 structure
2228857-30-3 structure
  • Name: Fmoc-NMe-PEG4-NHS este
  • Chemical Name: Fmoc-NMe-PEG4-NHS ester
  • CAS Number: 2228857-30-3
  • Molecular Formula: C31H38N2O10
  • Molecular Weight: 598.64
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 19:26:45
  • Modify Date: 2024-01-10 16:53:38
  • Fmoc-NMe-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Fmoc-NMe-PEG4-NHS ester
Description Fmoc-NMe-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C31H38N2O10
Molecular Weight 598.64