Fmoc-NMe-PEG4-NHS este

Modify Date: 2024-01-10 16:53:38

Fmoc-NMe-PEG4-NHS este Structure
Fmoc-NMe-PEG4-NHS este structure
Common Name Fmoc-NMe-PEG4-NHS este
CAS Number 2228857-30-3 Molecular Weight 598.64
Density N/A Boiling Point N/A
Molecular Formula C31H38N2O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Fmoc-NMe-PEG4-NHS este


Fmoc-NMe-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Fmoc-NMe-PEG4-NHS ester

 Fmoc-NMe-PEG4-NHS este Biological Activity

Description Fmoc-NMe-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C31H38N2O10
Molecular Weight 598.64