1189760-69-7

1189760-69-7 structure

1189760-69-7 structure

Name: HS-PEG3-CH2CH2NH2
Chemical Name: HS-PEG3-CH2CH2NH2
CAS Number: 1189760-69-7
Molecular Formula: C₈H₁₉NO₃S
Molecular Weight: 209.31
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 15:55:41
Modify Date: 2024-01-08 14:24:51
HS-PEG3-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	HS-PEG3-CH2CH2NH2

Description	HS-PEG3-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₈H₁₉NO₃S
Molecular Weight	209.31

Hazard Codes	Xi