Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Thiol-PEG5-Amine
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Purity: 98.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Thiol-PEG5-Amine
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Purity: 98.0%
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1347750-20-2

1347750-20-2 structure

1347750-20-2 structure

Name: Thiol-PEG5-Amine
Chemical Name: HS-PEG5-CH2CH2NH2
CAS Number: 1347750-20-2
Molecular Formula: C₁₂H₂₇NO₅S
Molecular Weight: 297.41
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 12:21:37
Modify Date: 2024-01-10 08:57:11
HS-PEG5-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	HS-PEG5-CH2CH2NH2
Synonyms	MFCD29052169

Description	HS-PEG5-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₂H₂₇NO₅S
Molecular Weight	297.41

Hazard Codes	Xi

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