874820-38-9

874820-38-9 structure

874820-38-9 structure

Name: m-PEG16-SH
Chemical Name: m-PEG16-SH
CAS Number: 874820-38-9
Molecular Formula: C₃₃H₆₈O₁₆S
Molecular Weight: 752.95
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 19:51:47
Modify Date: 2024-01-05 10:37:33
m-PEG16-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	m-PEG16-SH

Description	m-PEG16-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₃₃H₆₈O₁₆S
Molecular Weight	752.95