m-PEG16-SH

Modify Date: 2024-01-05 10:37:33

m-PEG16-SH structure	Common Name	m-PEG16-SH
	CAS Number	874820-38-9	Molecular Weight	752.95
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₃H₆₈O₁₆S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of m-PEG16-SH

m-PEG16-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	m-PEG16-SH

Description	m-PEG16-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₃₃H₆₈O₁₆S
Molecular Weight	752.95