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105108-59-6

105108-59-6 structure
105108-59-6 structure
  • Name: m-PEG3-4-nitrophenyl carbonate
  • Chemical Name: m-PEG2-4-nitrophenyl carbonate
  • CAS Number: 105108-59-6
  • Molecular Formula: C12H15NO7
  • Molecular Weight: 285.25
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 19:35:17
  • Modify Date: 2024-01-11 00:55:51
  • m-PEG2-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG2-4-nitrophenyl carbonate
Description m-PEG2-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C12H15NO7
Molecular Weight 285.25