m-PEG3-4-nitrophenyl carbonate

Modify Date: 2024-01-11 00:55:51

m-PEG3-4-nitrophenyl carbonate Structure
m-PEG3-4-nitrophenyl carbonate structure
Common Name m-PEG3-4-nitrophenyl carbonate
CAS Number 105108-59-6 Molecular Weight 285.25
Density N/A Boiling Point N/A
Molecular Formula C12H15NO7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG3-4-nitrophenyl carbonate


m-PEG2-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG2-4-nitrophenyl carbonate

 m-PEG3-4-nitrophenyl carbonate Biological Activity

Description m-PEG2-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C12H15NO7
Molecular Weight 285.25