Shanghai Nianxing Industrial Co., Ltd
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Product Name: M-Peg3-sulfone-peg2-oh
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Purity: 98.0%
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1919045-00-3

1919045-00-3 structure

1919045-00-3 structure

Name: M-Peg3-sulfone-peg2-oh
Chemical Name: m-PEG3-Sulfone-PEG3
CAS Number: 1919045-00-3
Molecular Formula: C₁₃H₂₈O₈S
Molecular Weight: 344.42
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 11:31:09
Modify Date: 2024-01-09 16:42:28
m-PEG3-Sulfone-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	m-PEG3-Sulfone-PEG3
Synonyms	MFCD29918251

Description	m-PEG3-Sulfone-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₃H₂₈O₈S
Molecular Weight	344.42

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