M-Peg3-sulfone-peg2-oh

Modify Date: 2024-01-09 16:42:28

M-Peg3-sulfone-peg2-oh Structure
M-Peg3-sulfone-peg2-oh structure
Common Name M-Peg3-sulfone-peg2-oh
CAS Number 1919045-00-3 Molecular Weight 344.42
Density N/A Boiling Point N/A
Molecular Formula C13H28O8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of M-Peg3-sulfone-peg2-oh


m-PEG3-Sulfone-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG3-Sulfone-PEG3
Synonym More Synonyms

 M-Peg3-sulfone-peg2-oh Biological Activity

Description m-PEG3-Sulfone-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C13H28O8S
Molecular Weight 344.42

 Synonyms

MFCD29918251