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2028284-71-9

2028284-71-9 structure
2028284-71-9 structure
  • Name: m-PEG6-(CH2)8-phosphonic acid
  • Chemical Name: m-PEG6-(CH2)6-Phosphonic acid
  • CAS Number: 2028284-71-9
  • Molecular Formula: C19H41O9P
  • Molecular Weight: 444.50
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 09:38:59
  • Modify Date: 2024-01-11 10:58:32
  • m-PEG6-(CH2)6-Phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG6-(CH2)6-Phosphonic acid
Synonyms MFCD30458009
Description m-PEG6-(CH2)6-Phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C19H41O9P
Molecular Weight 444.50