Top Suppliers:I want be here

2112737-70-7

2112737-70-7 structure
2112737-70-7 structure
  • Name: m-PEG8-(CH2)12-phosphonic acid ethyl ester
  • Chemical Name: m-PEG8-(CH2)12-phosphonic acid ethyl ester
  • CAS Number: 2112737-70-7
  • Molecular Formula: C31H65O11P
  • Molecular Weight: 644.81
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 18:31:49
  • Modify Date: 2024-01-12 20:16:53
  • m-PEG8-(CH2)12-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG8-(CH2)12-phosphonic acid ethyl ester
Synonyms MFCD30730359
Description m-PEG8-(CH2)12-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C31H65O11P
Molecular Weight 644.81