m-PEG8-(CH2)12-phosphonic acid ethyl ester

Modify Date: 2024-01-12 20:16:53

m-PEG8-(CH2)12-phosphonic acid ethyl ester Structure
m-PEG8-(CH2)12-phosphonic acid ethyl ester structure
Common Name m-PEG8-(CH2)12-phosphonic acid ethyl ester
CAS Number 2112737-70-7 Molecular Weight 644.81
Density N/A Boiling Point N/A
Molecular Formula C31H65O11P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG8-(CH2)12-phosphonic acid ethyl ester


m-PEG8-(CH2)12-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG8-(CH2)12-phosphonic acid ethyl ester
Synonym More Synonyms

  Biological Activity

Description m-PEG8-(CH2)12-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C31H65O11P
Molecular Weight 644.81

 Synonyms

MFCD30730359
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