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2101722-60-3

2101722-60-3 structure
2101722-60-3 structure
  • Name: Mal-amido-PEG12-NHS
  • Chemical Name: Mal-amido-PEG12-NHS ester
  • CAS Number: 2101722-60-3
  • Molecular Formula: C38H63N3O19
  • Molecular Weight: 865.92
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 21:08:45
  • Modify Date: 2025-09-06 20:35:47
  • Mal-amido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Mal-amido-PEG12-NHS ester
Synonyms MFCD11041148
Description Mal-amido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C38H63N3O19
Molecular Weight 865.92
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