Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Mal-NH-PEG12-CH2CH2COOPFP ester
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Purity: 97.0%
Stocking Period: 10 Day
Contact: Tom

2136296-33-6

2136296-33-6 structure

2136296-33-6 structure

Name: Mal-NH-PEG12-CH2CH2COOPFP ester
Chemical Name: Mal-NH-PEG12-CH2CH2COOPFP ester
CAS Number: 2136296-33-6
Molecular Formula: C₄₀H₅₉F₅N₂O₁₇
Molecular Weight: 934.89
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 18:43:42
Modify Date: 2024-01-13 15:59:41
Mal-NH-PEG12-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Mal-NH-PEG12-CH2CH2COOPFP ester

Description	Mal-NH-PEG12-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₄₀H₅₉F₅N₂O₁₇
Molecular Weight	934.89

Hazard Codes	Xi