1374666-31-5

1374666-31-5 structure

1374666-31-5 structure

Name: Mal-peg2-t-butyl ester
Chemical Name: Mal-PEG2-C2-Boc
CAS Number: 1374666-31-5
Molecular Formula: C₁₅H₂₃NO₆
Molecular Weight: 313.35
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 16:56:05
Modify Date: 2024-01-10 12:53:48
Mal-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Mal-PEG2-C2-Boc
Synonyms	MFCD23726621

Description	Mal-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₅H₂₃NO₆
Molecular Weight	313.35