2112737-19-4

2112737-19-4 structure
2112737-19-4 structure
  • Name: N-(Aminooxy-PEG3)-N-bis(PEG4-t-butyl ester)
  • Chemical Name: N-(Aminooxy-PEG3)-N-bis(PEG4-Boc)
  • CAS Number: 2112737-19-4
  • Molecular Formula: C38H76N2O16
  • Molecular Weight: 817.01
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-02 07:18:46
  • Modify Date: 2024-01-19 09:54:43
  • N-(Aminooxy-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-(Aminooxy-PEG3)-N-bis(PEG4-Boc)
Synonyms MFCD30730364
Description N-(Aminooxy-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C38H76N2O16
Molecular Weight 817.01
Hazard Codes Xi