2353409-90-0

2353409-90-0 structure
2353409-90-0 structure
  • Name: N-(Azido-PEG4)-N-bis(PEG4-NHS ester)
  • Chemical Name: N-(Azido-PEG4)-N-bis(PEG4-NHS ester)
  • CAS Number: 2353409-90-0
  • Molecular Formula: C41H68N6O21
  • Molecular Weight: 981.01
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 20:07:51
  • Modify Date: 2024-01-09 15:50:52
  • N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-(Azido-PEG4)-N-bis(PEG4-NHS ester)
Description N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C41H68N6O21
Molecular Weight 981.01
Hazard Codes Xi