2100306-75-8

2100306-75-8 structure
2100306-75-8 structure
  • Name: N-(Biotin)-N-bis(PEG1-alcohol)
  • Chemical Name: N-(Biotin)-N-bis(PEG1-alcohol)
  • CAS Number: 2100306-75-8
  • Molecular Formula: C18H33N3O6S
  • Molecular Weight: 419.54
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 10:43:15
  • Modify Date: 2024-01-31 15:14:47
  • N-(Biotin)-N-bis(PEG1-alcohol) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-(Biotin)-N-bis(PEG1-alcohol)
Synonyms MFCD29912796
Description N-(Biotin)-N-bis(PEG1-alcohol) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C18H33N3O6S
Molecular Weight 419.54