N-(Biotin)-N-bis(PEG1-alcohol)

Modify Date: 2024-01-31 15:14:47

N-(Biotin)-N-bis(PEG1-alcohol) Structure
N-(Biotin)-N-bis(PEG1-alcohol) structure
Common Name N-(Biotin)-N-bis(PEG1-alcohol)
CAS Number 2100306-75-8 Molecular Weight 419.54
Density N/A Boiling Point N/A
Molecular Formula C18H33N3O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(Biotin)-N-bis(PEG1-alcohol)


N-(Biotin)-N-bis(PEG1-alcohol) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-(Biotin)-N-bis(PEG1-alcohol)
Synonym More Synonyms

 N-(Biotin)-N-bis(PEG1-alcohol) Biological Activity

Description N-(Biotin)-N-bis(PEG1-alcohol) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C18H33N3O6S
Molecular Weight 419.54

 Synonyms

MFCD29912796