2093154-02-8

2093154-02-8 structure

2093154-02-8 structure

Name: N-Boc-n-bis(peg4-oh)
Chemical Name: N-Boc-N-bis-PEG5
CAS Number: 2093154-02-8
Molecular Formula: C₂₅H₅₁NO₁₂
Molecular Weight: 557.67
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 08:04:53
Modify Date: 2024-01-27 21:10:25
N-Boc-N-bis-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-Boc-N-bis-PEG5
Synonyms	MFCD30536157

Description	N-Boc-N-bis-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₅H₅₁NO₁₂
Molecular Weight	557.67