N-Boc-n-bis(peg4-oh)

Modify Date: 2024-01-27 21:10:25

N-Boc-n-bis(peg4-oh) Structure
N-Boc-n-bis(peg4-oh) structure
Common Name N-Boc-n-bis(peg4-oh)
CAS Number 2093154-02-8 Molecular Weight 557.67
Density N/A Boiling Point N/A
Molecular Formula C25H51NO12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Boc-n-bis(peg4-oh)


N-Boc-N-bis-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-Boc-N-bis-PEG5
Synonym More Synonyms

 N-Boc-n-bis(peg4-oh) Biological Activity

Description N-Boc-N-bis-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C25H51NO12
Molecular Weight 557.67

 Synonyms

MFCD30536157