2218463-36-4

2218463-36-4 structure

2218463-36-4 structure

Name: tert-Butyl (35-hydroxy-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontyl)carbamate
Chemical Name: N-Boc-PEG12-alcohol
CAS Number: 2218463-36-4
Molecular Formula: C₂₉H₅₉NO₁₄
Molecular Weight: 645.78
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 22:12:59
Modify Date: 2024-01-09 21:15:39
N-Boc-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-Boc-PEG12-alcohol
Synonyms	MFCD11041098

Description	N-Boc-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₉H₅₉NO₁₄
Molecular Weight	645.78

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