tert-Butyl (35-hydroxy-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontyl)carbamate

Modify Date: 2024-01-09 21:15:39

tert-Butyl (35-hydroxy-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontyl)carbamate Structure
tert-Butyl (35-hydroxy-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontyl)carbamate structure
Common Name tert-Butyl (35-hydroxy-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontyl)carbamate
CAS Number 2218463-36-4 Molecular Weight 645.78
Density N/A Boiling Point N/A
Molecular Formula C29H59NO14 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of tert-Butyl (35-hydroxy-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontyl)carbamate


N-Boc-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-Boc-PEG12-alcohol
Synonym More Synonyms

  Biological Activity

Description N-Boc-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C29H59NO14
Molecular Weight 645.78

 Synonyms

MFCD11041098