2055042-60-7

2055042-60-7 structure
2055042-60-7 structure
  • Name: N-(Boc-PEG3)-N-bis(PEG2-alcohol)
  • Chemical Name: N-(Boc-PEG3)-N-bis(PEG2-alcohol)
  • CAS Number: 2055042-60-7
  • Molecular Formula: C25H52N2O11
  • Molecular Weight: 556.69
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 14:14:45
  • Modify Date: 2024-01-05 14:32:10
  • N-(Boc-PEG3)-N-bis(PEG2-alcohol) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-(Boc-PEG3)-N-bis(PEG2-alcohol)
Synonyms MFCD30182039
Description N-(Boc-PEG3)-N-bis(PEG2-alcohol) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C25H52N2O11
Molecular Weight 556.69
Hazard Codes Xi