2093152-78-2

2093152-78-2 structure
2093152-78-2 structure
  • Name: N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester
  • Chemical Name: N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester
  • CAS Number: 2093152-78-2
  • Molecular Formula: C25H45NO9
  • Molecular Weight: 503.63
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 09:30:04
  • Modify Date: 2024-01-10 19:21:52
  • N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester
Synonyms MFCD30723293
Description N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C25H45NO9
Molecular Weight 503.63
Hazard Codes Xi