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2112737-60-5

2112737-60-5 structure
2112737-60-5 structure
  • Name: N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl)
  • Chemical Name: N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl)
  • CAS Number: 2112737-60-5
  • Molecular Formula: C29H52N2O11
  • Molecular Weight: 604.73
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 17:58:25
  • Modify Date: 2024-01-09 13:20:08
  • N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl)
Synonyms MFCD30730360
Description N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C29H52N2O11
Molecular Weight 604.73
Hazard Codes Xi